Fairfax County Police said the call came in about 10:05 p.m. The couple told police they were in the lower level of their single family home when they heard footsteps above.
The couple went upstairs to find an unknown man leaving through the sliding glass door, said police spokeswoman Lucy Caldwell.
Police called out the K9 unit and the helicopter, and a search for the suspect in the Glade Drive area ensued.
The suspect, who got away with cash and some other household items, has not yet been located. The homeowners were not injured, Caldwell said.
Police said the intruder may have entered through an unlocked door, so FCPD wants to remind residents to always keep doors locked and their eyes open.