The chain has 13 other locations in Northern Virginia, including one in Herndon.
Mathnasium offers math help for students in elementary school through high school.
Permits for interior alterations at 2260 Hunters Woods Plaza were filed last week. In August, Reston Tailoring vacated its storefront at Hunters Woods after 30 years at that location when it could not reach lease terms with plaza management. Reston Tailoring moved to Lake Anne Plaza.
No opening date for Mathnasium has been set.