The campaign will open an office at 1635 Washington Plaza, a former hair salon storefront at Lake Anne Plaza.
The office is expected to open soon, with a grand opening party later this month, a campaign spokesman said.
In 2012, Barack Obama’s re-election campaign had an office in Reston in an office building at 1760 Reston Parkway.
Local offices are where campaigns organize volunteers, hold phone banks and do other community-level campaign work.
Voters in Reston traditionally vote heavily Democratic in presidential elections. In 2008, Barack Obama won Reston precincts 66 percent to 33 percent. In 2012, Obama had 65 percent of the votes to Mitt Romney’s 34 percent.